Pharmacology Sample Paper

ER20-21T 2nd Year / Pharmacy. Time: 3 M.M.: 80 Sample 1.

SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 Who is the father of medicine? a) Hippocrates b) Galen c) Berg d) Landsteiner

• Q.2 The major side effect of chloramphenicol is?

  a) Nausea b) Bone Marrow Depression c) Vomiting d) Headache

• Q.3 Eno, Gelusil, and Digene are which type of drugs?

  a) Anti-histamines b) Anti-depressants c) Antacids d) Diuretics

• Q.4 Example of anti-emetic drugs

  a) Ondansetron b) Propanolol c) Hydrochlorthalidone d) Salbutamol

• Q.5 Which anti-epileptic drug is administered by intranasal route?

  a) Midazolam b) Diazepam c) Clobazam d) Nitrazepam

• Q.6 Which of the following is also known as Emergency Hormone?

  a) Cortisol b) Adrenaline c) Prolactin d) ADH

• Q.7 An antibiotic drug will be effective against which of the following diseases

  a) Dengue b) Influenza c) Cholera d) Hepatitis

• Q.8 The liver is the major organ for _______ of drugs

  a) Absorption b) Distribution c) Metabolism d) Excretion

• Q.9 The substances produced by or derived from living organisms that are used to kill bacteria or prevent their multiplication is called__________.

  a) Antibiotics b) Hormones c) Antidotes d) Enzymes

• Q.10 Drugs are excreted from the body through _______

  a) Kidney b) Intestines c) Sweat d) All of the above

• Q.11 Nitroglycerine is administered by which route?

  a) By parenteral route b) By sublingual route c) By inhalation d) By insertion

• Q.12 Drugs used to destroy and expel worms are known as_______.

  a) Antibiotics b) Anti-inflammatory c) Anti-helminthics d) Antipruritics

• Q.13 Drugs that dilate the blood vessels and are used to lower blood pressure are known as ________.

  a) Vasodilators b) Vasoconstrictors c) Mydriatics d) Myotics

• Q.14 Which route of drug administration will be preferred for an unconscious patient?

  a) Oral ingestion b) Inhalation c) Enteral d) Intravenous

• Q.15 5% Glucose Saline means __________.

  a) Each 100 ml contains 5gm glucose and 5gm sodium chloride

  b) Each 100 ml contains 5gm glucose and 0.9gm sodium chloride

  c) Each 100 ml contains 5gm glucose and 0.4gm sodium chloride

  d) Each 100 ml contains 0.5gm glucose and 0.9gm sodium chloride

• Q.16 An agent used to increase the level of haemoglobin content in the blood is known as __________.

  a) Hematinic b) Hemostatic c) Oxytocic d) Diuretic

• Q.17 The largest herbarium in the world is located in ________.

  a) Royal Botanical Garden, Kew b) Central National Herbarium, Shibpur

  c) Museum of Natural History, Paris d) Madras Herbarium, Coimbatore

• Q.18 Which of the following is a Selective Serotonin Reuptake Inhibitor?

  a) Selegiline b) Fluoxetine c) Bupropion d) Doxepin

• Q.19 Which of the following is an anti-anginal drug?

  a) Diltiazem b) Propranolol c) Nitroglycerin d) All of the above

• Q.20 Which of the following is not an aminoglycoside antibiotic?

  a) Steptomycin b) Neomycin c) Kanamycin d) Cephalexin

SECTION-B Note: Short answer type question. Attempt any ten questions out of Eleven questions. (10x3=30)

• Q.21 Define bioavailability and factors influencing bioavailability.

• Q.22 Write a brief note on pilocarpine.

• Q.23 Write a short note on an Anti-depressant drug

• Q.24 Briefly describe the drug paracetamol.

• Q.25 Briefly explain the treatment of shock.

• Q.26 Describe the pharmacological action and contraindications of streptokinase.

• Q.27 Define Bronchodilators and mention any two such drugs.

• Q.28 What is the best medicine to treat stomach ulcers? Mention any two drugs belonging to this class.

• Q.29 Briefly describe the drug Quinine.

• Q.30 Briefly describe the pharmacology of penicillin.

• Q.31 Write a short note on Autocoids.

SECTION-C Note: Long Answer Type Question. Attempt any six questions. (6x5=30)

• Q.32 Define and classify sulfonamides. Briefly describe the Pharmacology of these drugs with two suitable examples.

• Q.33 Define and classify Opioid Analgesics. Describe the pharmacology & contraindications with a suitable example.

• Q.34 Describe in detail the physiological & pathological role and clinical uses of Insulin.

• Q.35 Describe in detail the advantages and disadvantages associated with the parenteral Route of Administration.

• Q.36 Define and classify Cholinergic drugs Elaborate on the pharmacological action and contraindications of any one cholinergic drug.

• Q.37 Describe the pharmacological action of any two.

• a) Anti-Hypertensive Drugs b) Anti-Neoplastic drugs c) Anti-Fungal Drugs d) Estrogens

• Q.38 Define and classify anti-tubercular drugs. Describe briefly any one anti-tubercular drug.

Sample 2 Pharmacology ER20-21T 2nd Year/Pharmacy Time: 3 Hrs. M.M.: 80

SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 Aspirin belongs to which class of drugs?

  a) Nonsteroidal anti-inflammatory drugs (NSAIDs) b) Antibiotics

  c) Antidepressants d) Antipyretics

• Q.2 ACE inhibitors are primarily used to treat:

  a) Bacterial infections b) Diabetes c) Hypertension d) Allergic reactions

• Q.3 What is the primary function of anticoagulant drugs?

  a) Lowering blood pressure b) Reducing inflammation

  c) Preventing blood clot formation d) Stimulating insulin production

• Q.4 The term " antipyretic" refers to drugs that:

  a) Lower fever b) Increase body temperature c) Induce sleep d) Relieve pain

• Q.5 Clopidogrel is a medication primarily used to:

  a) Treat depression b) Prevent blood clot formation c) Lower cholesterol d) Treat diabetes

• Q.6 Which of the following is a common side effect of corticosteroid use?

  a) Hypertension b) Hypoglycemia c) Immune suppression d) Diarrhea

• Q.7 Which drug class is commonly used to treat depression and anxiety disorders?

  a) Benzodiazepines b) Antipsychotics

  c) Selective serotonin reuptake inhibitors (SSRIs) d) Antibiotics

• Q.8 In Parkinson's disease, which neurotransmitter is deficient and often targeted for drug therapy?

  a) Serotonin b) Dopamine c) GABA d) Acetylcholine

• Q.9 Which drug class is used to dilate blood vessels and lower blood pressure?

  a) Diuretics b) Beta-blockers c) Calcium channel blockers d) Antihistamines

• Q.10 Which drug is commonly used to treat allergic reactions?

  a) Cimetidine b) Metformin c) Diphenhydramine d) Omeprazole

• Q.11 The time it takes for the body to eliminate one-half of the drug's concentration is known as the drug's______.

• Q.12 The therapeutic index is a measure of a drug's ______.

• Q.13 Acetaminophen is an analgesic and______ but not an NSAID.

• Q.14 In pharmacology, GABA stands for__________.

• Q.15 Simvastatin is commonly used to treat high_______ levels.

• Q.16 Define the term Oxytocic agents.

• Q.17 Define the term Prodrugs.

• Q.18 What is Drug Efficacy?

• Q.19 Define a Placebo Effect.

• Q.20 Define Drug Clearance.

SECTION-B

Short answer type questions. Attempt any ten questions out of eleven questions. (10x3=30)

• Q.21 Explain the role of antihistamines in the treatment of allergies and allergic reactions.

• Q.22 Discuss the use of mucolytic agents in the treatment of cough.

• Q.23 Describe the classification of antibiotics based on their mechanism of action.

• Q.24 Explain the difference between over-the-counter (OTC) and prescription drugs.

• Q.25 Classify Neuro Muscular Blocking Agent with two examples each.

• Q.26 Discuss the mechanism of action and clinical uses of angiotensin receptor blockers (ARBs)

• Q.27 Define pharmacodynamics and describe the different types of drug receptors.

• Q.28 Classify Opioid analgesics with two examples each.

• Q.29 Describe the mechanism of action and therapeutic uses of antipsychotic drugs.

• Q.30 Explain the concept of bioavailability and its importance in drug administration

• Q.31 Classify Laxative and Purgative with two examples each.

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe the mechanisms of action, clinical uses, and potential side effects of angiotensin-converting enzyme (ACE) inhibitors in the treatment of cardiovascular conditions.

• Q.33 Explain the mechanism of action, clinical uses, and potential side effects of selective serotonin reuptake inhibitors (SSRIs) in the treatment of mood disorders.

• Q.34 Explain the pharmacological properties and clinical uses of diuretic medications in the management of hypertension and oedema.

• Q.35 Describe the importance of the kidneys in drug elimination and excretion, highlighting the role of glomerular filtration and tubular secretion.

• Q.36 Discuss the Causative microorganisms of Malaria and drugs used in the treatment of Malaria.

• Q.37 Describe the four major pharmacokinetic processes (absorption, distribution, metabolism, elimination) and their importance in drug therapy.

• Q.38 Discuss the mechanism of action and clinical applications of bronchodilators in the management of asthma.

Alok Bains

Sample 3 Pharmacology ER20-21T Time: 3 Hrs. M.M.: 80 2nd Year/Pharmacy

SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 What is the primary mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)?

  a) Enhancement of GABAergic neurotransmission

  b) Inhibition of cyclooxygenase (COX) enzymes

  c) Blockade of beta-adrenergic receptors d) Activation of opioid receptors

• Q.2 Which class of drugs is commonly used to treat hypertension and heart failure by inhibiting the renin-angiotensin-aldosterone system (RAAS)?

  a) Beta-Blockers b) Calcium channel blockers

  c) Angiotensin-converting enzyme (ACE) inhibitors d) Diuretics

• Q.3 Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI) commonly used to treat depression and anxiety disorders?

  a) Diazepam b) Paroxetine c) Morphine d) Warfarin

• Q.4 Which neurotransmitter is primarily targeted by benzodiazepines, leading to their anxiolytic and sedative effects?

  a) Serotonin b) Dopamine c) GABA (gamma-aminobutyric acid) d) Norepinephrine

• Q.5 What is the mechanism of action of statins in the treatment of hypercholesterolemia?

  a) Inhibition of HMG-CoA reductase b) Activation of lipoprotein lipase

  c) Blockade of histamine receptors d) Enhancement of bile acid synthesis

• Q.6 Which class of drugs is commonly used to relieve pain and induce anaesthesia by blocking sodium channels in nerve cells?

  a) Opioids b) Non-steroidal anti-inflammatory drugs (NSAIDs)

  c) Local anesthetics d) Antihistamines

• Q.7 Which drug is an antagonist at the mu-opioid receptor and is used to reverse the effects of opioid overdose?

• a) Naloxone b) Diazepam c) Furosemide d) Albuterol

• Q.8 Which type of diuretic is known to inhibit the reabsorption of sodium and chloride in the distal convoluted tubule of the kidney?

  a) Thiazide diuretics b) Loop diuretics

  c) Potassium-sparing diuretics d) Carbonic anhydrase inhibitors

• Q.9 Which of the following medications is commonly used to treat gastroesophageal reflux disease (GERD) by reducing stomach acid production?

  a) Metoprolol b) Renitidine c) Acetaminophen d) Insulin

• Q.10 Which class of drugs is used to treat bacterial infections by inhibiting cell wall synthesis a) Statins b) Beta-blockers c) Macrolides d) Penicillins

• Q.11 Define the term expectorant.

• Q.12 Define the term nootropics agent.

• Q.13 Define the term Tocolytic.

• Q.14 Give one example of a direct-acting cholinergic agonist.

• Q.15 What is the primary function of sodium bicarbonate when added to local anesthetic solutions?

• Q.16 The process by which a drug is absorbed, distributed, metabolized, and eliminated from the body is known as_________.

• Q.17 The primary site of drug metabolism in the body is the _______.

• Q.18 The study of how genetic factors influence an individual's response to drugs is called__________.

• Q.19 Proton pump inhibitors (PPIs) reduce stomach acid production by inhibiting the proton pump in the _____ cells of the stomach.

• Q.20 _____ is a class of drugs that reduce inflammation and pain by inhibiting the production of prostaglandins

SECTION-B

Short answer type questions. Attempt any ten questions out of eleven questions. (10x3=30)

• Q.21 Write a short note on drugs used in Myasthenia Gravis.

• Q.22 Write five physiological responses of Histamine.

• Q.23 Explain the concept of drug absorption and discuss factors that can influence drug absorption in the body.

• Q.24 Describe the difference between an agonist and an antagonist in the context of pharmacology. Provide an example of each.

• Q.25 Describe the mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) and provide examples of common NSAIDs and their uses.

• Q.26 Briefly explain the term "bioavailability" and discuss factors that can affect the bioavailability of a drug.

• Q.27 Briefly explain types of Adverse Drug Reactions.

• Q.28 Describe the mechanisms of action and common uses of bronchodilators in the treatment of respiratory conditions.

• Q.29 List three different routes of drug administration and provide an example of a drug suitable for each route.

• Q.30 Discuss the pharmacological mechanisms of action and clinical uses of antiplatelet agents, with an emphasis on aspirin and clopidogrel.

• Q.31 Differentiate between local anaesthetics and general anaesthetics, including their routes of administration and mechanisms of action.

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe three major classes of oral hypoglycaemic agents used in the management of type 2 diabetes mellitus. For each class, discuss their mechanisms of action and clinical indications.

• Q.33 Explain the pharmacological basis of antiemetic drugs used to manage nausea and vomiting. Describe three major classes of antiemetics and their mechanism of action.

• Q.34 Explain the pharmacological classification of cholinergic drugs and their mechanisms of action. Provide examples of drugs in each category and discuss their clinical applications in the management of various medical conditions.

• Q.35 Write a short note on glaucoma disease including its types and classify the drugs used in glaucoma.

• Q.36 Differentiate the terms psychosis and neurosis. Differentiate typical and atypical antipsychotics with four examples each.

• Q.37 Classify Anti-arrhythmic drugs and their pharmacological actions.

• Q.38 Classify Beta-lactam antibiotics and write indications of penicillin.

Alok Bains

Sample-4. Pharmacology ER20-21T 2nd Year/Branch: Pharmacy, Time Allowed: 3 Hrs. MM: 80

Section –A

Multiple Choice/Objective type questions. All questions are compulsory. 20x1=20

• Q.1 Which one is not an example of General anaesthetics

  (A) Procaine (B) Nitrous Oxide (C) Halothane (D) Ether

• Q.2 Which one drug is used to treat Myasthenia Gravis

  (A) Insulin (B) Penicillin (C) Heparin (D) Neostigmine

• Q.3 Example of Acetic acid derivative used as NSAIDS is

  (A) Indomethacin (B) Aspirin (C) Vitamins (D) Paracetamol

• Q.4 Which one is not a Cholinergic drug

  (A) Pilocarpine (B) Adrenaline (C) Physostigmine (D) Carbachol

• Q.5 Drug Haloperidol is used as

  (A) Antibiotics (B) Anti-Cancer drug (C) Anti leprotic Drug (D) Antipsychotic Drug

• Q.6 Mechanism of action of drug Verapamil includes

  (A) Ca++ Channel Blocks (B) Cell wall rapture (C) DNA Inhibition (D) Cell membrane rapture

• Q.7 Which one is the use of the drug insulin

  (A) Anti-cancer (B) Anti Diabetics (C) Haematinics (D) Local Anesthetics

• Q.8 Which one is the example of H-2 Receptor antagonists

  (A) Ranitidine (B) Aspirin (C) Methotrexate (D) Atropine

• Q.9 An Example of an alkylating agent anti-cancer drug is

  (A) Propranolol (B) Kanamycin (C) Nystatin (D) Cyclophosphamide

• Q.10. Example of Osmotic Diuretics is

  (A) Tolbutamide (B) Penicillin (C) Mannitol (D) Indomethacin

• Q.11 Define the term Pharmacology

• Q.12 Mention the mechanism of action of the drug penicillin

• Q.13 Mention one Heparin antagonist

• Q.14 Mention one use of Aspirin

• Q.15 Mention one use of Liquid Paraffin

• Q.16 Mention one example of Loop Diuretics

• Q.17 Define the term hypokalemia

• Q.18 Mention one use of Prochlorperazine

• Q.19 Mention the Mechanism of action of the Drug Methotrexate

• Q.20 Mention one example of Coagulants

Section-B

Short answer type Questions. Attempt any ten questions out of eleven questions. 10x3=30

• Q.21 Describe in brief Acetylcholine

• Q.22 Describe in brief one antispasmodic drug

• Q.23 Mention three uses of Gentamycin

• Q.24 Mention three uses of Quinine

• Q.25 Mention three adverse effects of Atropine

• Q.26 Mention three uses of Chlorpromazine

• Q.27 Briefly Describe three Pharmacological actions of Amphetamine

• Q.28 Briefly describe the Pharmacology of Cephalosporins

• Q.29 Briefly describe the drug Paracetamol.

• Q.30 Briefly describe the drug Diazepam

• Q.31 Briefly describe the drug Levodopa.

Section –C

Note: Long answer questions. Attempt any six questions out of seven questions. 6x5= 30

• Q.32 Define and classify Antibiotics, and briefly describe the pharmacology of Macrolides with two suitable examples

• Q.33 Define and classify Diuretics, Describe in brief Furosemide and Acetazolamide

• Q.34 Describe the Pharmacology of Vitamin D

• Q.35 Define and classify Anti Parkinson's drugs. Describe briefly about two anti-Parkinson drugs.

• Q.36 Define and classify Antiarrhythmic drugs. Describe briefly Quinidine and Diltiazem

• Q.37 Describe in brief Oral Hypoglycemic agents

• Q.38 Describe the Parenteral route of drug administration.