Biochemistry & Clinical Pathology Sample Paper HSBTE, MSBTE, UPSBTE, and Exit Examinations

Sample Paper 1: Biochemistry & Clinical Pathology ER20-23T 2nd Yr/ Pharm Time: 3 Hrs. M.M.: 80

SECTION-A

One-word/Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 The condition in which the colour of the sclera of the eyes and skin becomes yellow?

  a) Jaundice b) Yellow fever c) Plaque d) Congo fever

• Q.2 Bile salts are absent in? a) Pancreas b) Intestine c) Urine d) Stomach

• Q.3 Write the full form of VLDL.

• Q.4 _____ is known as cane sugar.

• Q.5 The normal life span of RBC is? a) 10 days b) 120 days c) 200 days d) 100 days

• Q.6 Enzymes responsible for the citric acid cycle are found in?

  a) Nucleus b) Ribosomes c) Mitochondria d) ER

• Q.7 Direction of DNA synthesis is __________.

• Q.8 Proteins undergo breakdown into smaller units called ____________.

• Q.9 Write the full form of PUFA

• Q.10 How many amino acids make a protein? a) 10 b) 30 c) 40 d) 20

• Q.11 Which factor is not responsible for denaturation of proteins?

  a) PH b) Heat c) Charge d) Organic solvent

• Q.12 Complex IV / Complex 4 is also known as ______.

• Q.13 Any substance that contains free ions with the property of electrical conductance is known as? a) Electrolyte b) Vitamins c) Proteins d) Mineral

• Q.14 In_____ tissue culture techniques were developed. a) 1905 b) 1908 c) 1907 d) 1900

• Q.15 The normal range of prothrombin time is?

  a) 1-6 seconds b) 12-16 seconds c) 12-16 minutes d) 12-16 hours

• Q.16 Which blood cells secrete antibodies?

  a) Eosinophils b) Monocytes c) Lymphocytes d) Neutrophils

• Q.17 The monomer unit of lipid is? a) Glucose b) Fatty acids c) Ribonucleotides d) Amino acid

• Q.18 Which one of the following is a non-reducing sugar?

  a) Maltose b) Mannose c) Sucrose d) Lactose

• Q.19 What color is Ninhydrin test?

  a) Blue to violet b) Blue to black c) Blue to green d) Blue to brown

• Q.20 Aldolase belongs to which class of enzymes______.

SECTION-B

Short answer type questions. Attempt any ten questions out of Eleven questions. (10x3=30)

• Q.21 Define Enzymes. Mentions its IUB classification.

• Q.22 Mention types of RNA and their functions

• Q.23 Give the structure of: a) Glucose c) Galactose b) Fructose

• Q.24 Define nucleic acid. Give the difference between nucleosides and nucleotides.

• Q.25 Define proteins. Give biological signification of proteins.

• Q.26 What are essential amino acids? Give an example and mention its significance.

• Q.27 What is alkaptonuria? Mention its causes, symptoms and treatments.

• Q.28 List the dietary sources of electrolytes.

• Q.29 Write about the role of platelets in health and disease.

• Q.30 Define Glycogenolysis and Glycogenesis. Give its significance.

• Q.31 What is oral rehydration therapy?

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe the urea cycle

• Q.33 Elaborate the normal and abnormal constituents of urine including their significance and laboratory tests to detect them.

• Q.34 Explain the factors affecting enzyme activity

• Q.35 Give the stricture of sucrose and maltose along with the test to identify them.

• Q.36 Mention the dietary sources, functions and deficiency manifestation of vitamin A.

• Q.37 Describe the scope of biochemistry in pharmacy.

• Q.38 Write a note on a disease related to abnormal metabolism of amino acids.

Sample Paper 2. Biochemistry & Clinical Pathology ER20-23T Time:3 Hrs. M.M.:80 2nd Year./Pharmacy

SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 Which one is the example of Monosaccharides a) Glucose b) Maltose c) Lactose d) Sucrose

• Q.2 Which one is not an example of Polysaccharides a) Starch b) Cellulose c) Heparin d) Fructose

• Q.3 Benedict's test is used for the identification of a) Carbohydrates b) Protein c) Vitamins d) Lipids

• Q.4 Fehling A Reagent contains a) Copper Sulphate b) Acetic Acid c) Cellulose d) Iodine

• Q.5 Which one is not an Essential Amino acid a) Leucine b) Valine c) Lysine d) Glycine.

• Q.6 The Ninhydrin test is used for the identification of a) Amino Acid b) Carbohydrates c) Lipids d) Vitamins

• Q.7 Enzyme Dehydrogenase is used for diagnosis of a) Myocardial Infarction b) Tuberculosis c) Hepatitis d) Diabetes

• Q.8 Deficiency of Iodine may cause a) Goiter b) Anemia c) Diabetes d) Hepatitis

• Q.9 Which one is the function of the kidney a) Removal of waste product b) Removal of excess fluid c) Control of Blood Pressure d) All of the above

• Q.10 Biotechnology has contributed to which area a) Medicine b) Industrial c) Environment d) all of the above

• Q.11 Define the term Biochemistry

• Q.12 The Sakaguchi test, a qualitative test, is used to identify what.

• Q.13 Define the term Enzyme

• Q.14 Mention one use of Iron

• Q.15 In Aerobic Glycolysis net gain of how much ATP occurs.

• Q.16 Define the term Hyperammonemia

• Q.17 Define the term Thrombocytopenia

• Q.18 Mention one use of Vitamin E

• Q.19 Full form of VLDL is

• Q.20 Mention one example of a Simple Lipid

SECTION-B

Short answer type questions. Attempt any ten questions out of eleven questions. (10x3=30)

• Q.21 Mention three scopes of Biochemistry in Pharmacy

• Q.22 Classify Disaccharides

• Q.23 Write a brief note on the disease Marasmus

• Q.24 Write a note on the Millions Test

• Q.25 Mention three functions of Lipoprotein

• Q.26 Mention three functions of RNA

• Q.27 Mention three properties of Enzymes

• Q.28 Mention three functions of Vitamin D

• Q.29 Mention the names of three glycogen storage diseases.

• Q.30 Mention three uses of Selenium

• Q.31 Mention three functions of water in the human body

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe in detail about Glycolysis.

• Q.33 Describe in detail any three Chemical properties of carbohydrates

• Q.34 Describe in detail about classification of Amino Acids

• Q.35 Describe in detail about factors affecting Enzyme activity

• Q.36 Describe in detail about Biochemistry of vitamins A, C & B12

• Q.37 Describe in detail the Biochemical role of Manganese and Cobalt

• Q.38 Describe in detail any two Abnormal Constituents of urine including their identification test and Biomedical importance.

Alok Bains

Sample Paper 3, Biochemistry and Clinical Pathology ER20-23T Time: 3 Hrs. M.M.: 80 2nd Year/Pharmacy

SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 Which one is an example of conjugated Protein

  a) Albumin b) Fructose c) Glycoprotein d) Globulins

• Q.2 Which one is an example of Reducing Sugar

  a) Albumins b) cellulose c) Starch d) Lactose

• Q.3 The Iodine test is used for the identification of

  a) Carbohydrates b) Protein c) Vitamins d) Lipids

• Q.4 Dipeptide contains

  a) 2-amino acid units b) 5-Amino acid units c) 9-amino acid units d) 7-amino acid units

• Q.5 Which one is not an example of fat

  a) Butter b) Fat c) Beef fat d) Olive oil

• Q.6 Which one is not an example of Waxes

  a) Butter b) Lanoline c) Beeswax d) Carnauba Wax

• Q.7 RNA does not contain

  a) Thymine b) Adenine c) Guanine d) Cytocine

• Q.8 Which one is Xerophthol or retinol

  a) Glucose b) Vitamin D c) Vitamin A d) Vitamin C

• Q.9 Net gain of ATP in aerobic Glycolysis

  a) 1 ATP b) 7 ATP c) 5 ATP d) 8 ATP

• Q.10 Which one Vitamin is known as an antiaging or inter-sterility factor

  a) Vitamin E b) Vitamin D c) Vitamin K d) Vitamin B6

• Q.11 Define the term Monosaccharides

• Q.12 Saliwanoffs, a qualitative test is used for identification of what.

• Q.13 Define the term Osteoporosis.

• Q.14 Mention one use of Vitamin C.

• Q.15 Define the term Lipids.

• Q.16 Define the term Nucleotide

• Q.17 Mention one use of Iodine

• Q.18 Mention one use of Calcium

• Q.19 Define the term Coenzyme

• Q.20 Mention the Full form of the ALP Test

SECTION-B

Short answer type questions. Attempt any ten questions out of eleven questions. (10x3=30)

• Q.21 Write a brief note on Hyperammonemia

• Q.22 Write a brief note on Jaundice

• Q.23 Mention three biological roles of Amino Acids

• Q.24 Mention three uses of Vitamin C Q.25 Mention three functions of Phosphorus

• Q.26 Mention three functions of Water in the Human Body

• Q.27 Mention three differences between Competitive and non-competitive Enzyme inhibition

• Q.28 Write a brief note on Oral rehydration Therapy

• Q.29 Write three functions of the Liver

• Q.30 Write a brief note on the Clinical significance of the Lipid profile test

• Q.31 Write a brief note on the Benzidine test

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe in detail about Glycolysis.

• Q.33 Write a brief note on the Definition, importance & Scope of Biochemistry

• Q.34 Describe in brief the Classification of Lipids

• Q.35 Describe in detail about Therapeutic Importance of Enzymes Q.36 Describe in detail about Biochemistry of Vitamin A, D & K

• Q.37 Write a detailed note on the structure and function of RNA

• Q.38 Write a detailed note on the disease.

Alok Bains

Sample Paper 4. Biochemistry & Clinical Pathology ER20-23T 2nd Year Pharmacy Time: 3 Hrs. M.M: 80

(SECTION-A Note: Multiple choice questions. All questions are compulsory (20x1=20)

• Q.1 Which one is an example of Disaccharides a) Glucose b) Fructose c) Lactose d) Starch

• Q.2 Which one is not an example of a Simple Protein a) Albumins b) Globulins c) Histones d) Glycoprotein

• Q.3 The Molisch test is used for the identification of

  a) Carbohydrates b) Protein c) Vitamins d) Lipids

• Q.4 Fehling B Reagent contains

  a) Sodium Potassium tartrate b) Acetic Acid c) Cellulose d) Iodine

• Q.5 Which one is not an Essential Amino acid a) Tryptophan b) Valine c) Lysine d) Alanine

• Q.6 All Enzymes are a) Protein b) Vitamins c) Minerals d) Lipids

• Q.7 Cholecalciferol is name of

  a) Vitamin D b) Vitamin A c) Vitamin B12 d) Vitamin C

• Q.8 Which one is the end product of the Metabolism of Amino Acids

  a) Glucose b) Fructose c) Urea d) Insulin

• Q.9 Which one is not an example of Compound Lipids

  a) Phospholipids b) Glycolipids c) Lipoproteins d) Waxes

• Q.10 Saponification test is used for the identification of

  a) Lipids b) Protein c) Carbohydrates d) Amino Acids Q.11 Define the term Carbohydrates

• Q.12 Barfoed's test, a qualitative test is used for identification of what.

• Q.13 Define the term Glycoprotein

• Q.14 Mention one use of Vitamin K

• Q.15 In Anaerobic Glycolysis net gain of how much ATP occurs.

• Q.16 Define the term Glycogenolysis Q.17 Define the term Alkaptonuria

• Q.18 Mention one use of Vitamin B-1

• Q.19 Define the term Coenzyme

• Q.20 Mention one example of Derived Lipids

SECTION-B

Short answer type questions. Attempt any ten questions out of eleven questions. (10x3=30)

• Q.21 Mention three contributions of Biotechnology

• Q.22 Mention three functions of the Liver

• Q.23 Mention three General properties of Amino Acids

• Q.24 Mention three uses of vitamin B-12

• Q.25 Mention three functions of Fluorine

• Q.26 Mention three functions of Nucleic Acid

• Q.27 Mention three Differences between Competitive and non-competitive Enzyme inhibition

• Q.28 Mention three Biological roles of Protein

• Q.29 Write a brief note on the disease kwashiorkor

• Q.30 Mention the Biochemical role of Creatinine

• Q.31 Mention three factors affecting Enzymes activity

SECTION-C

Long answer type questions. Attempt any six questions out of seven questions. (6x5=30)

• Q.32 Describe in detail about TCA Cycle

• Q.33 Describe in detail the structure of the Protein

• Q.34 Describe in brief the classification of Lipids with suitable examples

• Q.35 Describe in detail about Therapeutic Importance of Enzymes

• Q.36 Describe in detail about Biochemistry of vitamin D, E & B -6

• Q.37 Describe in detail about Urea Cycle Q.38 Describe in detail the Dehydration causes, Symptoms, type, and Oral rehydration therapy.

Alok Bains